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Regulatory T-cell Transcriptomic Reprogramming Characterizes Adverse Events by Checkpoint Inhibitors in Solid Tumors.

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第一作者： Maria,Grigoriou

第一单位： Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation Academy of Athens, Athens, Greece.

作者： Maria,Grigoriou ^[1] ; Aggelos,Banos ^[1] ; Aikaterini,Hatzioannou ^[1] ; Andreas,Kloetgen ^[2] ; Panagiotis,Kouzis ^[3] ; Despoina,Aggouraki ^[4] ; Roubini,Zakopoulou ^[5] ; Giorgos,Bamias ^[6] ; Eva,Kassi ^[7] ; Dimitrios,Mavroudis ^[4] ; Aristotelis,Bamias ^[5] ; Dimitrios T,Boumpas ^[8] ; Aristotelis,Tsirigos ^[9] ; Helen,Gogas ^[3] ; Themis,Alissafi ^[10] ; Panayotis,Verginis ^[11]

作者单位： Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation Academy of Athens, Athens, Greece. ^[1] Department of Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany. ^[2] First Department of Medicine, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece. ^[3] Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece. ^[4] Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, Athens, Greece. ^[5] GI-Unit, 3rd Academic Department of Internal Medicine, Sotiria Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. ^[6] Endocrinology Unit, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece. ^[7] Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation Academy of Athens, Athens, Greece.;Joint Rheumatology Program, 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece. ^[8] Department of Pathology, New York University Grossman School of Medicine, New York, New York. ^[9] Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation Academy of Athens, Athens, Greece. talissafi@bioacademy.gr pverginis@uoc.gr. ^[10] Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Greece. talissafi@bioacademy.gr pverginis@uoc.gr.;Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, University of Crete Medical School, Heraklion, Greece. ^[11]

医学主题词成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);女(雌)性(Female);人类(Humans);免疫耐受(Immune Tolerance);免疫表型分型(Immunophenotyping);男(雄)性(Male);黑色素瘤(Melanoma);中年人(Middle Aged);皮肤肿瘤(Skin Neoplasms);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);青年人(Young Adult)

DOI 10.1158/2326-6066.CIR-20-0969

PMID 33820810

发布时间 2025-05-30

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Regulatory T-cell Transcriptomic Reprogramming Characterizes Adverse Events by Checkpoint Inhibitors in Solid Tumors.

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Regulatory T-cell Transcriptomic Reprogramming Characterizes Adverse Events by Checkpoint Inhibitors in Solid Tumors.

Cancer immunology research

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