Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.

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第一作者： Omar M,Khan

第一单位： Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK. okhan@hbku.edu.qa.;Hamad Bin Khalifa University, College of Health and Life Sciences Qatar Foundation, Education City, Education City, Doha, Qatar. okhan@hbku.edu.qa.

作者： Omar M,Khan ^[1] ; Jorge,Almagro ^[2] ; Jessica K,Nelson ^[2] ; Stuart,Horswell ^[3] ; Vesela,Encheva ^[4] ; Kripa S,Keyan ^[5] ; Bruce E,Clurman ^[6] ; Ambrosius P,Snijders ^[4] ; Axel,Behrens ^[7]

作者单位： Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK. okhan@hbku.edu.qa.;Hamad Bin Khalifa University, College of Health and Life Sciences Qatar Foundation, Education City, Education City, Doha, Qatar. okhan@hbku.edu.qa. ^[1] Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK. ^[2] Bioinformatics and Biostatistics, London, UK. ^[3] Proteomics, The Francis Crick Institute, London, UK. ^[4] Hamad Bin Khalifa University, College of Health and Life Sciences Qatar Foundation, Education City, Education City, Doha, Qatar. ^[5] Fred Hutchinson Cancer Research Center, Seattle, WA, USA. ^[6] Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK. axel.behrens@icr.ac.uk.;Cancer Stem Cell Laboratory, Institute of Cancer Research, London, UK. axel.behrens@icr.ac.uk.;Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK. axel.behrens@icr.ac.uk.;Convergence Science Centre, Imperial College London, London, UK. axel.behrens@icr.ac.uk. ^[7]