Efficient antiglioblastoma therapy in mice through doxorubicin-loaded nanomicelles modified using a novel brain-targeted RVG-15 peptide.-论文-万方医学网

作者： Mingfeng,Han ^[1] ; Haoyue,Xing ^[2] ; Liqing,Chen ^[1] ; Minhu,Cui ^[3] ; Yingying,Zhang ^[1] ; Lingling,Qi ^[1] ; Mingji,Jin ^[1] ; Yang,Yang ^[4] ; Chunsheng,Gao ^[4] ; Zhonggao,Gao ^[1] ; Xuezhong,Xing ^[5] ; Wei,Huang ^[1]

作者单位： Department of Pharmaceutics, State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ^[1] Beijing No.2 Middle School, Beijing, China. ^[2] Yanbian University Hospital, Jilin, China. ^[3] State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China. ^[4] National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ^[5]

主题词动物(Animals);抗生素类, 抗肿瘤(Antibiotics, Antineoplastic);细胞凋亡(Apoptosis);血脑屏障(Blood-Brain Barrier);脑肿瘤(Brain Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);多柔比星(Doxorubicin);药物载体(Drug Carriers);药物释放系统(Drug Delivery Systems);胶质母细胞瘤(Glioblastoma);糖蛋白类(Glycoproteins);豚鼠(Guinea Pigs);小鼠(Mice);小鼠, 近交ICR(Mice, Inbred ICR);微胶粒(Micelles);纳米粒子(Nanoparticles);粒子大小(Particle Size);肽碎片(Peptide Fragments);大鼠(Rats);组织分布(Tissue Distribution);病毒蛋白质类(Viral Proteins)

DOI 10.1080/1061186X.2021.1912053

PMID 33825602

发布时间 2022-02-15

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Efficient antiglioblastoma therapy in mice through doxorubicin-loaded nanomicelles modified using a novel brain-targeted RVG-15 peptide.

Journal of drug targeting

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Journal of drug targeting

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Efficient antiglioblastoma therapy in mice through doxorubicin-loaded nanomicelles modified using a novel brain-targeted RVG-15 peptide.

Journal of drug targeting

相似文献

Journal of drug targeting

相关期刊

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