作者:
Stefan C,Dentro [1]
;
Ignaty,Leshchiner [2]
;
Kerstin,Haase [3]
;
Maxime,Tarabichi [4]
;
Jeff,Wintersinger [5]
;
Amit G,Deshwar [5]
;
Kaixian,Yu [6]
;
Yulia,Rubanova [5]
;
Geoff,Macintyre [7]
;
Jonas,Demeulemeester [8]
;
Ignacio,Vázquez-García [9]
;
Kortine,Kleinheinz [10]
;
Dimitri G,Livitz [2]
;
Salem,Malikic [11]
;
Nilgun,Donmez [12]
;
Subhajit,Sengupta [13]
;
Pavana,Anur [14]
;
Clemency,Jolly [3]
;
Marek,Cmero [15]
;
Daniel,Rosebrock [2]
;
Steven E,Schumacher [2]
;
Yu,Fan [6]
;
Matthew,Fittall [3]
;
Ruben M,Drews [7]
;
Xiaotong,Yao [16]
;
Thomas B K,Watkins [17]
;
Juhee,Lee [18]
;
Matthias,Schlesner [19]
;
Hongtu,Zhu [6]
;
David J,Adams [20]
;
Nicholas,McGranahan [21]
;
Charles,Swanton [22]
;
Gad,Getz [23]
;
Paul C,Boutros [24]
;
Marcin,Imielinski [16]
;
Rameen,Beroukhim [25]
;
S Cenk,Sahinalp [11]
;
Yuan,Ji [26]
;
Martin,Peifer [27]
;
Inigo,Martincorena [20]
;
Florian,Markowetz [7]
;
Ville,Mustonen [28]
;
Ke,Yuan [29]
;
Moritz,Gerstung [30]
;
Paul T,Spellman [14]
;
Wenyi,Wang [6]
;
Quaid D,Morris [31]
;
David C,Wedge [32]
;
Peter,Van Loo [33]
;
PCAWG Evolution and Heterogeneity Working Group and the PCAWG Consortium
作者单位:
Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK; Big Data Institute, University of Oxford, Oxford OX3 7LF, UK.
[1]
Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
[2]
Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
[3]
Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.
[4]
University of Toronto, Toronto, ON M5S 3E1, Canada; Vector Institute, Toronto, ON M5G 1L7, Canada.
[5]
The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
[6]
Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK.
[7]
Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Human Genetics, University of Leuven, 3000 Leuven, Belgium.
[8]
Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK; University of Cambridge, Cambridge CB2 0QQ, UK; Computational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA.
[9]
German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Heidelberg University, 69120 Heidelberg, Germany.
[10]
Cancer Data Science Laboratory, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
[11]
Simon Fraser University, Burnaby, BC V5A 1S6, Canada; Vancouver Prostate Centre, Vancouver, BC V6H 3Z6, Canada.
[12]
NorthShore University HealthSystem, Evanston, IL 60201, USA.
[13]
Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR 97231, USA.
[14]
University of Melbourne, Melbourne, VIC 3010, Australia; Walter + Eliza Hall Institute, Melbourne, VIC 3000, Australia.
[15]
Weill Cornell Medicine, New York, NY 10065, USA; New York Genome Center, New York, NY 10013, USA.
[16]
Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
[17]
University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
[18]
German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
[19]
Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.
[20]
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London WC1E 6BT, UK; Cancer Genome Evolution Research Group, University College London Cancer Institute, London WC1E 6DD, UK.
[21]
Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London WC1E 6BT, UK; Department of Medical Oncology, University College London Hospitals, London NW1 2BU, UK.
[22]
Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129, USA; Massachusetts General Hospital, Department of Pathology, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02215, USA.
[23]
University of Toronto, Toronto, ON M5S 3E1, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada; University of California, Los Angeles, Los Angeles, CA 90095, USA.
[24]
Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[25]
NorthShore University HealthSystem, Evanston, IL 60201, USA; The University of Chicago, Chicago, IL 60637, USA.
[26]
Department of Translational Genomics, Center for Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931 Cologne, Germany.
[27]
Organismal and Evolutionary Biology Research Programme, Department of Computer Science, Institute of Biotechnology, University of Helsinki, 00014 Helsinki, Finland.
[28]
Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK; School of Computing Science, University of Glasgow, Glasgow G12 8RZ, UK.
[29]
Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge CB10 1SD, UK; European Molecular Biology Laboratory, Genome Biology Unit, 69117 Heidelberg, Germany.
[30]
University of Toronto, Toronto, ON M5S 3E1, Canada; Vector Institute, Toronto, ON M5G 1L7, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada; Computational and Systems Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
[31]
Big Data Institute, University of Oxford, Oxford OX3 7LF, UK; Oxford NIHR Biomedical Research Centre, Oxford OX4 2PG, UK; Manchester Cancer Research Centre, University of Manchester, Manchester M20 4GJ, UK.
[32]
Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK. Electronic address: peter.vanloo@crick.ac.uk.
[33]
主题词
DNA拷贝数变异(DNA Copy Number Variations);DNA, 肿瘤(DNA, Neoplasm);数据库, 遗传学(Databases, Genetic);抗药性, 肿瘤(Drug Resistance, Neoplasm);遗传异质性(Genetic Heterogeneity);人类(Humans);肿瘤(Neoplasms);多态性, 单核苷酸(Polymorphism, Single Nucleotide)
DOI
10.1016/j.cell.2021.03.009
PMID
33831375
发布时间
2024-08-09
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Cell
Cell
2239-2254.e39页
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