Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin.

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作者： Mawar,Karsa ^[1] ; Angelika,Kosciolek ^[2] ; Angelika,Bongers ^[1] ; Anna,Mariana ^[2] ; Tim,Failes ^[1] ; Andrew J,Gifford ^[2] ; Ursula R,Kees ^[1] ; Laurence C,Cheung ^[2] ; Rishi S,Kotecha ^[3] ; Greg M,Arndt ^[1] ; Michelle,Haber ^[2] ; Murray D,Norris ^[3] ; Rosemary,Sutton ^[1] ; Richard B,Lock ^[2] ; Michelle J,Henderson ^[4] ; Klaartje,Somers ^[5]

作者单位： Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia. ^[1] School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia. ^[2] 2ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia. ^[3] Department of Anatomical Pathology, Prince of Wales Hospital, Randwick, NSW, Australia. ^[4] Division of Children's Leukaemia and Cancer Research, Telethon Kids Cancer Centre, Telethon Kids Institute, University of Western Australia, Perth, WA, Australia. ^[5] School of Pharmacy and Biomedical Sciences, Curtin University, Perth, WA, Australia. ^[6] Department of Haematology and Oncology, Perth Children's Hospital, Perth, WA, Australia. ^[7] Division of Paediatrics, School of Medicine, University of Western Australia, Perth, WA, Australia. ^[8] UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, NSW, Australia. ^[9] Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia. mhenderson@ccia.unsw.edu.au. ^[10] School of Women's and Children's Health, UNSW Sydney, Sydney, NSW, Australia. mhenderson@ccia.unsw.edu.au. ^[11]