换一批Development of a method for generating SNP interaction-aware polygenic risk scores for radiotherapy toxicity.
第一作者：
Nicola Rares,Franco
第一单位：
MOX, Department of Mathematics, Politecnico di Milano, Italy. Electronic address: nicolarares.franco@polimi.it.
作者：
Nicola Rares,Franco [1]
;
Michela Carlotta,Massi [2]
;
Francesca,Ieva [3]
;
Andrea,Manzoni [4]
;
Anna Maria,Paganoni [5]
;
Paolo,Zunino [6]
;
Liv,Veldeman [7]
;
Piet,Ost [8]
;
Valérie,Fonteyne [9]
;
Christopher J,Talbot [10]
;
Tim,Rattay [11]
;
Adam,Webb [12]
;
Kerstie,Johnson [13]
;
Maarten,Lambrecht [14]
;
Karin,Haustermans [15]
;
Gert,De Meerleer [16]
;
Dirk,de Ruysscher [17]
;
Ben,Vanneste [18]
;
Evert,Van Limbergen [19]
;
Ananya,Choudhury [20]
;
Rebecca M,Elliott [21]
;
Elena,Sperk [22]
;
Marlon R,Veldwijk [23]
;
Carsten,Herskind [24]
;
Barbara,Avuzzi [25]
;
Barbara,Noris Chiorda [26]
;
Riccardo,Valdagni [27]
;
David,Azria [28]
;
Marie-Pierre,Farcy-Jacquet [29]
;
Muriel,Brengues [30]
;
Barry S,Rosenstein [31]
;
Richard G,Stock [32]
;
Ana,Vega [33]
;
Miguel E,Aguado-Barrera [34]
;
Paloma,Sosa-Fajardo [35]
;
Alison M,Dunning [36]
;
Laura,Fachal [37]
;
Sarah L,Kerns [38]
;
Debbie,Payne [39]
;
Jenny,Chang-Claude [40]
;
Petra,Seibold [41]
;
Catharine M L,West [42]
;
Tiziana,Rancati [43]
;
REQUITE Consortium Collaborators
作者单位：
MOX, Department of Mathematics, Politecnico di Milano, Italy. Electronic address: nicolarares.franco@polimi.it.
[1]
MOX, Department of Mathematics, Politecnico di Milano, Italy; CADS-Center for Analysis, Decisions and Society, Human Technopole, Milan, Italy. Electronic address: michelacarlotta.massi@polimi.it.
[2]
MOX, Department of Mathematics, Politecnico di Milano, Italy; CADS-Center for Analysis, Decisions and Society, Human Technopole, Milan, Italy; CHRP-National Center for Healthcare Research and Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy. Electronic address: francesca.ieva@polimi.it.
[3]
MOX, Department of Mathematics, Politecnico di Milano, Italy. Electronic address: andrea1.manzoni@polimi.it.
[4]
MOX, Department of Mathematics, Politecnico di Milano, Italy; CADS-Center for Analysis, Decisions and Society, Human Technopole, Milan, Italy; CHRP-National Center for Healthcare Research and Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy. Electronic address: anna.paganoni@polimi.it.
[5]
MOX, Department of Mathematics, Politecnico di Milano, Italy. Electronic address: paolo.zunino@polimi.it.
[6]
Department of Human Structure and Repair, Ghent University, Belgium; Department of Radiation Oncology, Ghent University Hospital, Belgium. Electronic address: liv.veldeman@ugent.be.
[7]
Department of Human Structure and Repair, Ghent University, Belgium; Department of Radiation Oncology, Ghent University Hospital, Belgium. Electronic address: piet.ost@ugent.be.
[8]
Department of Human Structure and Repair, Ghent University, Belgium; Department of Radiation Oncology, Ghent University Hospital, Belgium. Electronic address: valerie.fonteyne@uzgent.be.
[9]
Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, United Kingdom. Electronic address: cjt14@leicester.ac.uk.
[10]
Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, United Kingdom. Electronic address: tr104@leicester.ac.uk.
[11]
Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, United Kingdom. Electronic address: ajw51@leicester.ac.uk.
[12]
Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, United Kingdom. Electronic address: kj91@leicester.ac.uk.
[13]
Department of Radiation Oncology, University Hospitals Leuven, Belgium. Electronic address: maarten.lambrecht@uzleuven.be.
[14]
Department of Radiation Oncology, University Hospitals Leuven, Belgium. Electronic address: karin.haustermans@uzleuven.be.
[15]
Department of Radiation Oncology, University Hospitals Leuven, Belgium. Electronic address: gert.demeerleer@uzleuven.be.
[16]
Maastricht University Medical Center, the Netherlands; Department of Radiation Oncology (Maastro), GROW Institute for Oncology and Developmental Biology, Maastricht, the Netherlands. Electronic address: dirk.deruysscher@maastro.nl.
[17]
Department of Radiation Oncology (Maastro), GROW Institute for Oncology and Developmental Biology, Maastricht, the Netherlands. Electronic address: ben.vanneste@maastro.nl.
[18]
Maastricht University Medical Center, the Netherlands; Department of Radiation Oncology (Maastro), GROW Institute for Oncology and Developmental Biology, Maastricht, the Netherlands. Electronic address: evert.vanlimbergen@maastro.nl.
[19]
Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, UK. Electronic address: ananya.choudhury@nhs.net.
[20]
Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, UK. Electronic address: rebecca.m.elliott@manchester.ac.uk.
[21]
Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany. Electronic address: Elena.sperk@umm.de.
[22]
Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany. Electronic address: marlon.veldwijk@medma.uni-heidelberg.de.
[23]
Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany. Electronic address: Carsten.herskind@medma.uni-heidelberg.de.
[24]
Department of Radiation Oncology 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: barbara.avuzzi@istitutotumori.mi.it.
[25]
Department of Radiation Oncology 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: Barbara.Noris@istitutotumori.mi.it.
[26]
Department of Radiation Oncology 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Oncology and Haemato-Oncology, Università degli Studi di Milano, Milan, Italy; Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: riccardo.valdagni@istitutotumori.mi.it.
[27]
Department of Radiation Oncology, University Federation of Radiation Oncology, Montpellier Cancer Institute, Univ Montpellier MUSE, France. Electronic address: David.Azria@icm.unicancer.fr.
[28]
Department of Radiation Oncology, University Federation of Radiation Oncology, Institut de Cancérologie du Gard, Nimes, France. Electronic address: marie.pierre.farcy.jacquet@chu-nimes.fr.
[29]
Department of Radiation Oncology, University Federation of Radiation Oncology, Montpellier Cancer Institute, Univ Montpellier MUSE, France. Electronic address: muriel.brengues@icm.unicancer.fr.
[30]
Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, USA. Electronic address: Barry.Rosenstein@mssm.edu.
[31]
Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, USA. Electronic address: richard.stock@mssm.edu.
[32]
Grupo de Medicina Xenómica (USC), Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Biomedical Network on Rare Diseases (CIBERER), Spain. Electronic address: ana.vega@usc.es.
[33]
Grupo de Medicina Xenómica (USC), Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain. Electronic address: miguelelias.aguado@usc.es.
[34]
Grupo de Medicina Xenómica (USC), Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain. Electronic address: paloma.sosa.fajardo@sergas.es.
[35]
Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Labs, UK. Electronic address: amd24@medschl.cam.ac.uk.
[36]
Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Labs, UK; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. Electronic address: lf370@medschl.cam.ac.uk.
[37]
Departments of Radiation Oncology and Surgery, University of Rochester Medical Center, Rochester, USA. Electronic address: Sarah_Kerns@URMC.Rochester.edu.
[38]
Centre for Integrated Genomic Medical Research (CIGMR), University of Manchester, UK. Electronic address: Debbie.Payne@manchester.ac.uk.
[39]
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Germany. Electronic address: j.chang-claude@dkfz-heidelberg.de.
[40]
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: p.seibold@Dkfz-Heidelberg.de.
[41]
Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, UK. Electronic address: Catharine.West@manchester.ac.uk.
[42]
Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: Tiziana.rancati@istitutotumori.mi.it.
[43]
医学主题词
曲线下面积(Area Under Curve);人类(Humans);男(雄)性(Male);多态性, 单核苷酸(Polymorphism, Single Nucleotide);前列腺肿瘤(Prostatic Neoplasms);辐射损伤(Radiation Injuries);危险因素(Risk Factors)
DOI
10.1016/j.radonc.2021.03.024
PMID
33838170
发布时间
2025-05-30
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Radiotherapy and oncology
Radiotherapy and oncology
241-248页
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