Islet-on-a-chip: Biomimetic micropillar-based microfluidic system for three-dimensional pancreatic islet cell culture.

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第一作者： Patrycja,Sokolowska

第一单位： Medical Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Poland; Laboratory of Cell Signaling and Metabolic Disorders, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland.

作者： Patrycja,Sokolowska ^[1] ; Kamil,Zukowski ^[2] ; Justyna,Janikiewicz ^[3] ; Elzbieta,Jastrzebska ^[4] ; Agnieszka,Dobrzyn ^[3] ; Zbigniew,Brzozka ^[5]

作者单位： Medical Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Poland; Laboratory of Cell Signaling and Metabolic Disorders, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland. ^[1] Centre for Advanced Materials and Technologies CEZAMAT, Warsaw University of Technology, Poland. ^[2] Laboratory of Cell Signaling and Metabolic Disorders, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland. ^[3] Medical Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Poland. ^[4] Medical Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Poland. Electronic address: brzozka@ch.pw.edu.pl. ^[5]

关键词 Glucagon secretion Insulin secretion Islet-on-a-chip diabetes mellitus Lab-on-a-chip system Microfluidic system Pancreatic islet Three-dimensional cellular model