Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells.

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作者： Kazue,Terasawa ^[1] ; Yuji,Kato ^[2] ; Yuta,Ikami ^[3] ; Kensaku,Sakamoto ^[4] ; Kazumasa,Ohtake ^[4] ; Seisuke,Kusano ^[5] ; Yuri,Tomabechi ^[6] ; Mutsuko,Kukimoto-Niino ^[6] ; Mikako,Shirouzu ^[6] ; Jun-Lin,Guan ^[7] ; Toshihide,Kobayashi ^[8] ; Takanori,Iwata ^[2] ; Tetsuro,Watabe ^[1] ; Shigeyuki,Yokoyama ^[5] ; Miki,Hara-Yokoyama ^[1]

作者单位： Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan. ^[1] Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan. ^[2] Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan. ^[3] Laboratory for Nonnatural Amino Acid Technology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan. ^[4] RIKEN Cluster for Science, Technology and Innovation Hub, Yokohama, Japan. ^[5] Laboratory for Protein Function and Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan. ^[6] Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA. ^[7] Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Université de Strasbourg, Illkirch, France. ^[8]

关键词 Chaperone-mediated autophagy GAPDH-HT expanded genetic codes lysosomes photo-crosslinking protein assembly