换一批Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas.
第一作者：
Tuyu,Zheng
第一单位：
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.;Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
作者：
Tuyu,Zheng [1]
;
David R,Ghasemi [2]
;
Konstantin,Okonechnikov [2]
;
Andrey,Korshunov [3]
;
Martin,Sill [2]
;
Kendra K,Maass [4]
;
Patricia,Benites Goncalves da Silva [2]
;
Marina,Ryzhova [5]
;
Johannes,Gojo [6]
;
Damian,Stichel [7]
;
Amir,Arabzade [8]
;
Robert,Kupp [9]
;
Julia,Benzel [1]
;
Shinichiro,Taya [10]
;
Toma,Adachi [10]
;
Ryo,Shiraishi [10]
;
Nicolas U,Gerber [11]
;
Dominik,Sturm [12]
;
Jonas,Ecker [13]
;
Philipp,Sievers [7]
;
Florian,Selt [13]
;
Rebecca,Chapman [14]
;
Christine,Haberler [15]
;
Dominique,Figarella-Branger [16]
;
Guido,Reifenberger [17]
;
Gudrun,Fleischhack [18]
;
Stefan,Rutkowski [19]
;
Andrew M,Donson [20]
;
Vijay,Ramaswamy [21]
;
David,Capper [22]
;
David W,Ellison [23]
;
Christel C,Herold-Mende [24]
;
Ulrich,Schüller [25]
;
Sebastian,Brandner [26]
;
Pablo Hernáiz,Driever [27]
;
Johan M,Kros [28]
;
Matija,Snuderl [29]
;
Till,Milde [13]
;
Richard G,Grundy [14]
;
Mikio,Hoshino [10]
;
Stephen C,Mack [30]
;
Richard J,Gilbertson [31]
;
David T W,Jones [32]
;
Marcel,Kool [33]
;
Andreas,von Deimling [7]
;
Stefan M,Pfister [4]
;
Felix,Sahm [34]
;
Daisuke,Kawauchi [35]
;
Kristian W,Pajtler [36]
作者单位：
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.;Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
[1]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.
[2]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.
[3]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany.
[4]
Department of Neuropathology, NN Burdenko Neurosurgical Institute, Moscow, Russia.
[5]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Department of Pediatrics and Adolescent Medicine and Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria.
[6]
Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.
[7]
Department of Pediatrics, Division of Hematology and Oncology, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.;Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas.
[8]
Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom.
[9]
Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, NCNP, Tokyo, Japan.
[10]
Department of Oncology, University Children's Hospital, Zurich, Switzerland.
[11]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany.;Pediatric Glioma Research Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[12]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany.;Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK), Heidelberg, Germany.
[13]
Children's Brain Tumour Research Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
[14]
Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria.
[15]
Department of Pathology and Neuropathology, La Timone Hospital, Aix Marseille University, Marseille, France.
[16]
Institute of Neuropathology, Heinrich Heine University, Medical Faculty, Duesseldorf, Germany.;German Cancer Consortium (DKTK), Partner Site Essen/Duesseldorf, Germany.
[17]
Pediatric Oncology and Hematology, Pediatrics III, University Hospital of Essen, Essen, Germany.
[18]
Department of Paediatric Haematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[19]
University of Colorado Anschutz Medical Campus, Aurora, Colorado.
[20]
Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
[21]
Department of Neuropathology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.;German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[22]
Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
[23]
Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
[24]
Department of Paediatric Haematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.;Research Institute, Children's Cancer Center Hamburg, Hamburg, Germany.;Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[25]
Division of Neuropathology, UCL Queen Square Institute of Neurology and The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, United Kingdom.;Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
[26]
Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
[27]
Department of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands.
[28]
Division of Neuropathology, Department of Pathology, NYU Langone Health, New York, New York.
[29]
Department of Pediatrics, Division of Hematology and Oncology, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.
[30]
Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom.;Department of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, United Kingdom.
[31]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Pediatric Glioma Research Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[32]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.;Princess Máxima Centre for Paediatric Oncology, Utrecht, the Netherlands.
[33]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany. k.pajtler@kitz-heidelberg.de d.kawauchi@ncnp.go.jp felix.sahm@med.uni-heidelberg.de.;Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.
[34]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany. k.pajtler@kitz-heidelberg.de d.kawauchi@ncnp.go.jp felix.sahm@med.uni-heidelberg.de.;Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.;Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, NCNP, Tokyo, Japan.
[35]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany. k.pajtler@kitz-heidelberg.de d.kawauchi@ncnp.go.jp felix.sahm@med.uni-heidelberg.de.;Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany.
[36]
医学主题词
动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);DNA结合蛋白质类(DNA-Binding Proteins);疾病模型, 动物(Disease Models, Animal);室管膜瘤(Ependymoma);基因组学(Genomics);人类(Humans);小鼠(Mice);蛋白质类(Proteins);幕上肿瘤(Supratentorial Neoplasms);转录因子(Transcription Factors)
DOI
10.1158/2159-8290.CD-20-0963
PMID
33879448
发布时间
2025-05-30
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Cancer discovery
Cancer discovery
2230-2247页
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