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<i>In Vivo</i> Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection.

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第一作者： Helena Strand,Clemmensen

第一单位： Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark.;Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.

作者： Helena Strand,Clemmensen ^[1] ; Jean-Yves,Dube ^[2] ; Fiona,McIntosh ^[3] ; Ida,Rosenkrands ^[4] ; Gregers,Jungersen ^[1] ; Claus,Aagaard ^[4] ; Peter,Andersen ^[5] ; Marcel A,Behr ^[6] ; Rasmus,Mortensen ^[7]

作者单位： Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark.;Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark. ^[1] Department of Microbiology and Immunology, McGill University, Montréal, Canada.;Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montréal, Canada.;McGill International TB Centre, Montréal, Canada. ^[2] Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montréal, Canada.;McGill International TB Centre, Montréal, Canada. ^[3] Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark. ^[4] Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark.;Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark. ^[5] Department of Microbiology and Immunology, McGill University, Montréal, Canada.;Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montréal, Canada.;McGill International TB Centre, Montréal, Canada.;Department of Medicine, McGill University Health Centre, Montréal, Canada. ^[6] Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark rjm@ssi.dk. ^[7]

关键词 ESAT-6 MPT70 Mycobacterium tuberculosis T cell differentiation immunization in vivo expression vaccination