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Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.

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第一作者： Corvin D,Arveseth

第一单位： Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.

作者： Corvin D,Arveseth ^[1] ; John T,Happ ^[1] ; Danielle S,Hedeen ^[1] ; Ju-Fen,Zhu ^[1] ; Jacob L,Capener ^[1] ; Dana,Klatt Shaw ^[2] ; Ishan,Deshpande ^[3] ; Jiahao,Liang ^[3] ; Jiewei,Xu ^[4] ; Sara L,Stubben ^[1] ; Isaac B,Nelson ^[1] ; Madison F,Walker ^[1] ; Kouki,Kawakami ^[5] ; Asuka,Inoue ^[5] ; Nevan J,Krogan ^[4] ; David J,Grunwald ^[2] ; Ruth,Hüttenhain ^[4] ; Aashish,Manglik ^[3] ; Benjamin R,Myers ^[1]

作者单位： Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America. ^[1] Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America. ^[2] Department of Pharmaceutical Chemistry, Department of Anaesthesia and Perioperative Care, University of California, San Francisco, California, United States of America. ^[3] Department of Cellular and Molecular Pharmacology, Quantitative Biosciences Institute, University of California, San Francisco, California, United States of America.;J. David Gladstone Institutes, San Francisco, California, United States of America. ^[4] Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan. ^[5]