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Human brain region-specific variably methylated regions are enriched for heritability of distinct neuropsychiatric traits.

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第一作者: Lindsay F,Rizzardi
第一单位: Center for Epigenetics, Johns Hopkins University School of Medicine, 855 N. Wolfe St., Baltimore, MD, 21205, USA.;HudsonAlpha Institute for Biotechnology, 601 Genome Way, Huntsville, AL, 35806, USA.
作者单位: Center for Epigenetics, Johns Hopkins University School of Medicine, 855 N. Wolfe St., Baltimore, MD, 21205, USA.;HudsonAlpha Institute for Biotechnology, 601 Genome Way, Huntsville, AL, 35806, USA. [1] Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe St, Baltimore, MD, 21205, USA.;Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.;Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia. [2] Center for Epigenetics, Johns Hopkins University School of Medicine, 855 N. Wolfe St., Baltimore, MD, 21205, USA. [3] Center for Epigenetics, Johns Hopkins University School of Medicine, 855 N. Wolfe St., Baltimore, MD, 21205, USA.;Department of Pediatrics, Division of Infectious Diseases, University of Arkansas for Medical Sciences, 13 Children's Way, Little Rock, AR, 72202, USA.;Arkansas Children's Research Institute, Little Rock, AR, 72202, USA. [4] Center for Epigenetics, Johns Hopkins University School of Medicine, 855 N. Wolfe St., Baltimore, MD, 21205, USA.;Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD, 21205, USA. [5] Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, 615 N. Wolfe St, Baltimore, MD, 21205, USA. [6] Center for Epigenetics, Johns Hopkins University School of Medicine, 855 N. Wolfe St., Baltimore, MD, 21205, USA. khansen@jhsph.edu.;Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe St, Baltimore, MD, 21205, USA. khansen@jhsph.edu.;Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. khansen@jhsph.edu. [7] Center for Epigenetics, Johns Hopkins University School of Medicine, 855 N. Wolfe St., Baltimore, MD, 21205, USA. afeinberg@jhu.edu.;Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. afeinberg@jhu.edu.;Departments of Biomedical Engineering and Mental Health, Johns Hopkins University Schools of Engineering and Public Health, Baltimore, MD, USA. afeinberg@jhu.edu. [8]
DOI 10.1186/s13059-021-02335-w
PMID 33888138
发布时间 2024-05-04
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