PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome <i>via</i> Regulating Its Expression in Human Macrophages.

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作者： Takuya,Yashiro ^[1] ; Machiko,Yamamoto ^[1] ; Sanae,Araumi ^[1] ; Mutsuko,Hara ^[2] ; Kyoko,Yogo ^[3] ; Koichiro,Uchida ^[3] ; Kazumi,Kasakura ^[1] ; Chiharu,Nishiyama ^[1]

作者单位： Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Katsushika-Ku, Japan. ^[1] Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Bunkyo-ku, Japan. ^[2] Juntendo University Advanced Research Institute for Health Science, Bunkyo-ku, Japan. ^[3]

关键词 IRF8 N LRP3 PU.1 inflammasome macrophage

主题词动物(Animals);基因表达调控(Gene Expression Regulation);基因敲低技术(Gene Knockdown Techniques);人类(Humans);炎性体(Inflammasomes);干扰素调节因子类(Interferon Regulatory Factors);巨噬细胞(Macrophages);小鼠(Mice);启动区, 遗传(Promoter Regions, Genetic);原癌基因蛋白质类(Proto-Oncogene Proteins);种特异性(Species Specificity);反式激活因子类(Trans-Activators);U937细胞(U937 Cells)

DOI 10.3389/fimmu.2021.649572

PMID 33897697

发布时间 2021-09-27

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Frontiers in immunology

2021年12卷

649572页

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PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome <i>via</i> Regulating Its Expression in Human Macrophages.

Frontiers in immunology

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Frontiers in immunology

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PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome <i>via</i> Regulating Its Expression in Human Macrophages.

Frontiers in immunology

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Frontiers in immunology

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