Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m<sup>6</sup>A signaling.-论文-万方医学网

作者： Kaiju,Sun ^[1] ; Yangyang,Du ^[2] ; Yuzhu,Hou ^[1] ; Mingyue,Zhao ^[1] ; Jiajia,Li ^[3] ; Yazhe,Du ^[4] ; Lingxiao,Zhang ^[2] ; Changbao,Chen ^[1] ; Hongmei,Yang ^[1] ; Fei,Yan ^[2] ; Rui,Su ^[1]

作者单位： Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130017, China. ^[1] State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), International Research Center for Chemistry-Medicine Joint Innovation, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. ^[2] Department of Obstetrics and Gynecology, First Hospital, Jilin University, 130021, P. R. China. ^[3] Department of blood specialty, First Hospital, Jilin University, 130021, China. ^[4]

主题词腺苷(Adenosine);动物(Animals);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);HL-60细胞(HL-60 Cells);人类(Humans);K562细胞(K562 Cells);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);甲基化(Methylation);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, SCID(Mice, SCID);齐墩果酸(Oleanolic Acid);蛋白激酶抑制剂(Protein Kinase Inhibitors);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);RNA, 信使(RNA, Messenger);皂苷类(Saponins);信号传导(Signal Transduction);U937细胞(U937 Cells)

DOI 10.7150/thno.55574

PMID 33897884

发布时间 2024-08-09

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Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m<sup>6</sup>A signaling.

Theranostics

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Theranostics

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Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m<sup>6</sup>A signaling.

Theranostics

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Theranostics

相关期刊

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