Amino acids functionalized dendrimers with nucleus accumulation for efficient gene delivery.

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作者： Guoxin,Tan ^[1] ; Jiayang,Li ^[1] ; Dandan,Liu ^[2] ; Hao,Pan ^[3] ; Renfang,Zhu ^[1] ; Yue,Yang ^[1] ; Weisan,Pan ^[4]

作者单位： School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, PR China. ^[1] School of Biomedical & Chemical Engineering, Liaoning Institute of Science and Technology, Benxi 117004, PR China. ^[2] College of Pharmacy, Liaoning University, Shenyang 110036, PR China. ^[3] School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, PR China. Electronic address: pppwwwsss@163.com. ^[4]

关键词 Dendrimer Endosomal escape Gene delivery Nucleus accumulation

主题词氨基酸类(Amino Acids);树状聚合物(Dendrimers);基因转移技术(Gene Transfer Techniques);转染(Transfection)

DOI 10.1016/j.ijpharm.2021.120641

PMID 33901600

发布时间 2021-06-17

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