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首页> Peptides> C-peptide ameliorates high glucose-induced podocyte dysfunction through the regulation of the Notch and TGF-β signaling pathways.

C-peptide ameliorates high glucose-induced podocyte dysfunction through the regulation of the Notch and TGF-β signaling pathways.

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作者： Jiao,Luo ^[1] ; Jiahong,Jiang ^[2] ; Hongjian,Huang ^[3] ; Feifei,Jiang ^[2] ; Zeru,Xu ^[2] ; Zijun,Zhou ^[2] ; Hong,Zhu ^[4]

作者单位： Department of Laboratory Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China. ^[1] Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. ^[2] Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. ^[3] Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. Electronic address: zhuhong@wmu.edu.cn. ^[4]

关键词 C-peptide Notch signaling pathway Podocyte dysfunction TGF-β signaling pathway

主题词动物(Animals);C肽(C-Peptide);糖尿病, 实验性(Diabetes Mellitus, Experimental);糖尿病肾病(Diabetic Nephropathies);葡萄糖(Glucose);降血糖药(Hypoglycemic Agents);胰岛素(Insulin);胰岛移植(Islets of Langerhans Transplantation);男(雄)性(Male);足细胞(Podocytes);大鼠(Rats);大鼠, Wistar(Rats, Wistar);受体, Notch(Receptors, Notch);甜味剂(Sweetening Agents);转化生长因子β1(Transforming Growth Factor beta1)

DOI 10.1016/j.peptides.2021.170557

PMID 33901627

发布时间 2022-02-09

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