Amoeba Predation of Cryptococcus neoformans Results in Pleiotropic Changes to Traits Associated with Virulence.

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第一作者： Man Shun,Fu

第一单位： Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

作者： Man Shun,Fu ^[1] ; Livia C,Liporagi-Lopes ^[1] ; Samuel R,Dos Santos ^[2] ; Jennifer L,Tenor ^[1] ; John R,Perfect ^[3] ; Christina A,Cuomo ^[4] ; Arturo,Casadevall ^[4]

作者单位： Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. ^[1] Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. ^[2] Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil. ^[3] Division of Infectious Diseases, Department of Medicine and Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA. ^[4] Infectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA. ^[5] Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA acasade1@jhu.edu. ^[6]

关键词 Acanthamoeba castellanii Cryptococcus neoformans amoeba evolution host-pathogen interactions macrophages opportunistic fungi