UHPLC-MS/MS Method for Determination of Hydroxychloroquine and Its Main Metabolites in Oral Fluid and Whole Blood for Therapeutic Drug Monitoring.

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第一作者： Nilo J C,Duarte

第一单位： Central Laboratory Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.

作者： Nilo J C,Duarte ^[1] ; Léonard V K,Kupa ^[2] ; Julio C R,Ferreira-Filho ^[3] ; Nicole,Fontoura ^[3] ; Marc Y,Chalom ^[3] ; Paschoalina,Romano ^[1] ; Pérsio A R,Ebner ^[1] ; Clovis A A,Silva ^[2] ; Valdemir M,Carvalho ^[1] ; Eloisa,Bonfá ^[2]

作者单位： Central Laboratory Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil. ^[1] Laboratório de Investigação Médica (LIM 03), Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil. ^[2] Rheumatology Division Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil. ^[3] Grupo Fleury, Sao Paulo, SP, Brazil. ^[4]

关键词 hydroxychloroquine mass spectrometry method validation systemic lupus erythematosus therapeutic drug monitoring

主题词色谱法, 高压液相(Chromatography, High Pressure Liquid);药物监测(Drug Monitoring);人类(Humans);羟氯喹(Hydroxychloroquine);固相萃取(Solid Phase Extraction);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1093/jalm/jfab031

PMID 33907815

发布时间 2021-10-15

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The journal of applied laboratory medicine

2021年6卷4期

868-880页

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UHPLC-MS/MS Method for Determination of Hydroxychloroquine and Its Main Metabolites in Oral Fluid and Whole Blood for Therapeutic Drug Monitoring.

The journal of applied laboratory medicine

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The journal of applied laboratory medicine

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UHPLC-MS/MS Method for Determination of Hydroxychloroquine and Its Main Metabolites in Oral Fluid and Whole Blood for Therapeutic Drug Monitoring.

The journal of applied laboratory medicine

相似文献

The journal of applied laboratory medicine

相关期刊

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