首页> The Journal of clinical investigation> HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.

HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.

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第一作者： Rashi,Singhal

第一单位： Department of Molecular and Integrative Physiology.

作者： Rashi,Singhal ^[1] ; Sreedhar R,Mitta ^[1] ; Nupur K,Das ^[1] ; Samuel A,Kerk ^[2] ; Peter,Sajjakulnukit ^[3] ; Sumeet,Solanki ^[1] ; Anthony,Andren ^[3] ; Roshan,Kumar ^[4] ; Kenneth P,Olive ^[5] ; Ruma,Banerjee ^[4] ; Costas A,Lyssiotis ^[6] ; Yatrik M,Shah ^[6]

作者单位： Department of Molecular and Integrative Physiology. ^[1] Department of Internal Medicine, Division of Gastroenterology.;Rogel Cancer Center, and. ^[2] Rogel Cancer Center, and. ^[3] Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, USA. ^[4] Department of Pathology.;Division of Digestive and Liver Diseases, Department of Medicine, and.;Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, USA. ^[5] Department of Molecular and Integrative Physiology.;Department of Internal Medicine, Division of Gastroenterology.;Rogel Cancer Center, and. ^[6]

关键词 Cancer Cell stress Hypoxia Metabolism Oncology