首页> Pharmaceutics> Combination Therapy of Novel Oncolytic Adenovirus with Anti-PD1 Resulted in Enhanced Anti-Cancer Effect in Syngeneic Immunocompetent Melanoma Mouse Model.

Combination Therapy of Novel Oncolytic Adenovirus with Anti-PD1 Resulted in Enhanced Anti-Cancer Effect in Syngeneic Immunocompetent Melanoma Mouse Model.

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第一作者： Mariangela,Garofalo

第一单位： Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via F. Marzolo 5, 35131 Padova, Italy.

作者： Mariangela,Garofalo ^[1] ; Laura,Bertinato ^[1] ; Monika,Staniszewska ^[2] ; Magdalena,Wieczorek ^[3] ; Stefano,Salmaso ^[1] ; Silke,Schrom ^[4] ; Beate,Rinner ^[4] ; Katarzyna Wanda,Pancer ^[3] ; Lukasz,Kuryk ^[5]

作者单位： Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via F. Marzolo 5, 35131 Padova, Italy. ^[1] Centre for Advanced Materials and Technologies, Warsaw University of Technology, Poleczki 19, 02-822 Warsaw, Poland. ^[2] Department of Virology, National Institute of Public Health-National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. ^[3] Division of Biomedical Research, Medical University of Graz, Roseggerweg 48, 8036 Graz, Austria. ^[4] Department of Virology, National Institute of Public Health-National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland.;Clinical Science, Targovax Oy, Lars Sonckin kaari 14, 02600 Espoo, Finland. ^[5]

关键词 CD40L ICOSL PD-1 inhibitors combinatory therapy immunotherapy melanoma oncolytic adenovirus

DOI 10.3390/pharmaceutics13040547

PMID 33919827

发布时间 2021-05-18

基金项目

CA 17140/This publication is based upon work from COST Action "Cancer Nanomedicine from the Bench to the Bedside" supported by COST (European Cooperation in Science and Technology) GARO_SID19_02 (M.G.)/PRID-J funded by University of Padua 504/04496/1020/45.010406/Centre for Advanced Materials and Technologies, WUT, Poland and grant POB Biotechmed-1 (Excellence Initiative Research University) SONATINA (2019/32/C/NZ7/00156) (L.K.)/Narodowe Centrum Nauki 1BWBW/19 (L.K.)/National Institute of Public Health-National Institute of Hygiene, Poland

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