An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells.
第一作者:
Sihang,Yu
第一单位:
Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun 130000, China.
作者:
主题词
氨基酸序列(Amino Acid Sequence);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);顺铂(Cisplatin);女(雌)性(Female);己糖激酶(Hexokinase);人类(Humans);线粒体(Mitochondria);模型, 生物学(Models, Biological);突变(Mutation);卵巢肿瘤(Ovarian Neoplasms);磷酰化(Phosphorylation);蛋白质转运(Protein Transport);泛素(Ubiquitin);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);增量调节(Up-Regulation)
DOI
10.3390/ijms22083983
PMID
33924293
发布时间
2021-05-12
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