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首页> Development (Cambridge, England)> Cis-regulatory dissection of cone development reveals a broad role for Otx2 and Oc transcription factors.

Cis-regulatory dissection of cone development reveals a broad role for Otx2 and Oc transcription factors.

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作者： Nicolas,Lonfat ^[1] ; Su,Wang ^[2] ; ChangHee,Lee ^[3] ; Mauricio,Garcia ^[1] ; Jiho,Choi ^[1] ; Peter J,Park ^[2] ; Connie,Cepko ^[4]

作者单位： Department of Genetics, Blavatnik Institute; Harvard Medical School, Boston, MA 02115, USA.;Department of Ophthalmology, Blavatnik Institute; Harvard Medical School, Boston, MA 02115, USA. ^[1] Department of Biomedical Informatics, Blavatnik Institute; Harvard Medical School, Boston, MA 02115, USA. ^[2] Department of Genetics, Blavatnik Institute; Harvard Medical School, Boston, MA 02115, USA. ^[3] Department of Genetics, Blavatnik Institute; Harvard Medical School, Boston, MA 02115, USA.;Department of Ophthalmology, Blavatnik Institute; Harvard Medical School, Boston, MA 02115, USA.;Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA. ^[4]

关键词 Cis-regulatory module CRM Chick Chromatin Cone Enhancer GRN Gene regulatory network Horizontal cell Onecut Otx2 Photoreceptor Retina

主题词动物(Animals);结合部位(Binding Sites);鸡(Chickens);染色质(Chromatin);解剖(Dissection);基因表达调控, 发育期(Gene Expression Regulation, Developmental);基因调控网络(Gene Regulatory Networks);肝细胞核因子6(Hepatocyte Nuclear Factor 6);Otx转录因子类(Otx Transcription Factors);视网膜(Retina);视锥光感受器细胞(Retinal Cone Photoreceptor Cells);干细胞(Stem Cells);转录因子(Transcription Factors)

DOI 10.1242/dev.198549

PMID 33929509

发布时间 2024-09-10

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Development (Cambridge, England)

Development (Cambridge, England)

2021年148卷9期

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