Glaucocalyxin A suppresses osteoclastogenesis induced by RANKL and osteoporosis induced by ovariectomy by inhibiting the NF-κB and Akt pathways.

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作者： Meisong,Zhu ^[1] ; Jing,Shan ^[2] ; Huaen,Xu ^[3] ; Guoming,Xia ^[4] ; Qiang,Xu ^[5] ; Kun,Quan ^[6] ; Xuqiang,Liu ^[7] ; Min,Dai ^[8]

作者单位： Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi province, 330006, China. Electronic address: zhumeisongv@163.com. ^[1] Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi province, 330006, China. Electronic address: 454776398@qq.com. ^[2] Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi province, 330006, China. Electronic address: 18370655730@163.com. ^[3] Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi province, 330006, China. Electronic address: 510688327@qq.com. ^[4] Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi province, 330006, China. Electronic address: xuqiangyisheng@126.com. ^[5] Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi province, 330006, China. Electronic address: quankun201066@sina.cn. ^[6] Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi province, 330006, China. Electronic address: shliuxuqiang@163.com. ^[7] Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi province, 330006, China. Electronic address: daiminyisheng@163.com. ^[8]

关键词 Akt Glaucocalyxin A NF-κB Osteoclastogenesis Osteoporosis Ovariectomized mice