A Rationally Designed Bovine IgA Fc Scaffold Enhances in planta Accumulation of a VHH-Fc Fusion Without Compromising Binding to Enterohemorrhagic E. coli.

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第一作者： Adam,Chin-Fatt

第一单位： Agriculture and Agri-Food Canada, London Research and Development Centre, London, ON, Canada.;Department of Biology, University of Western Ontario, London, ON, Canada.

作者： Adam,Chin-Fatt ^[1] ; Reza,Saberianfar ^[2] ; Rima,Menassa ^[1]

作者单位： Agriculture and Agri-Food Canada, London Research and Development Centre, London, ON, Canada.;Department of Biology, University of Western Ontario, London, ON, Canada. ^[1] Agriculture and Agri-Food Canada, London Research and Development Centre, London, ON, Canada. ^[2]

关键词 Fc fusion IgA VHH antibody fragment enterohemorrhagic E. coli-EHEC plant-made antibodies rational design antibody engineering single domain antibody (sdAb)transient expression

DOI 10.3389/fpls.2021.651262

PMID 33936135

发布时间 2021-05-04

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