Long-Term Treatment with Telotristat Ethyl in Patients with Carcinoid Syndrome Symptoms: Results from the TELEPATH Study.

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第一作者： Dieter,Hörsch

第一单位： Department of Gastroenterology/Endocrinology, Center for Neuroendocrine Tumors, Zentralklinik Bad Berka, Bad Berka, Germany.

作者： Dieter,Hörsch ^[1] ; Lowell,Anthony ^[2] ; David J,Gross ^[3] ; Juan W,Valle ^[4] ; Staffan,Welin ^[5] ; Marta,Benavent ^[6] ; Martyn,Caplin ^[7] ; Marianne,Pavel ^[8] ; Emily,Bergsland ^[9] ; Kjell,Öberg ^[5] ; Kenneth B,Kassler-Taub ^[10] ; Polina,Binder ^[10] ; Phillip,Banks ^[10] ; Pablo,Lapuerta ^[10] ; Matthew H,Kulke ^[11]

作者单位： Department of Gastroenterology/Endocrinology, Center for Neuroendocrine Tumors, Zentralklinik Bad Berka, Bad Berka, Germany. ^[1] Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA. ^[2] Neuroendocrine Tumor Unit, Department of Medicine, Endocrine Service, European Neuroendocrine Tumor Society Center of Excellence, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. ^[3] University of Manchester/The Christie NHS Foundation Trust, Manchester, United Kingdom. ^[4] Department of Endocrine Oncology, Uppsala University Hospital, Uppsala, Sweden. ^[5] Medical Oncology Department, Virgen del Rocío University Hospital/Instituto de Biomedicina de Sevilla, Seville, Spain. ^[6] Department of Gastroenterology & Hepatobiliary Medicine, Royal Free Hospital, Pond Street Centre for Gastroenterology, London, United Kingdom. ^[7] Department of Gastroenterology and Hepatology, Charité-Universitätsmedizin, Berlin, Germany. ^[8] Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California, USA. ^[9] Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, USA. ^[10] Section of Hematology/Oncology, Boston University and Boston Medical Center, Boston, Massachusetts, USA. ^[11]

关键词 Carcinoid syndrome Diarrhea Quality of life Safety and tolerability Telotristat ethyl

主题词成年人(Adult);人类(Humans);恶性类癌综合征(Malignant Carcinoid Syndrome);苯丙氨酸(Phenylalanine);嘧啶类(Pyrimidines);生活质量(Quality of Life);治疗结果(Treatment Outcome)

DOI 10.1159/000516958

PMID 33940581

发布时间 2022-04-08

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准确一般字义偏差语意偏离译文作用小提交