DNA methylation profiling for molecular classification of adult diffuse lower-grade gliomas.

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作者： Sandra,Ferreyra Vega ^[1] ; Thomas,Olsson Bontell ^[2] ; Alba,Corell ^[3] ; Anja,Smits ^[4] ; Asgeir Store,Jakola ^[1] ; Helena,Carén ^[5]

作者单位： Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. ^[1] Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. ^[2] Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. ^[3] Department of Clinical Pathology and Cytology, Sahlgrenska University Hospital, Gothenburg, Sweden. ^[4] Department of Neurosurgery, Sahlgrenska University Hospital, Gothenburg, Sweden. ^[5] Department of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden. ^[6] Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. jakola.asgeir@gu.se. ^[7] Department of Neurosurgery, Sahlgrenska University Hospital, Gothenburg, Sweden. jakola.asgeir@gu.se. ^[8] Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway. jakola.asgeir@gu.se. ^[9] Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. helena.caren@gu.se. ^[10]

关键词 DNA methylation profiling DNA methylation-based classification Diffuse lower-grade glioma Molecular classification Prognosis