Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils.

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第一作者： Camilla,Margaroli

第一单位： Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.;Center for CF & Airways Disease Research, Children's Healthcare of Atlanta, Atlanta, GA, USA.

作者： Camilla,Margaroli ^[1] ; Diego,Moncada-Giraldo ^[1] ; Dalia Arafat,Gulick ^[2] ; Brian,Dobosh ^[1] ; Vincent D,Giacalone ^[1] ; Osric A,Forrest ^[1] ; Fangxu,Sun ^[3] ; Chunhui,Gu ^[1] ; Amit,Gaggar ^[4] ; Haydn,Kissick ^[5] ; Ronghu,Wu ^[3] ; Greg,Gibson ^[2] ; Rabindra,Tirouvanziam ^[1]

作者单位： Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.;Center for CF & Airways Disease Research, Children's Healthcare of Atlanta, Atlanta, GA, USA. ^[1] School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA. ^[2] Department of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA. ^[3] Department of Medicine, Division of Pulmonary, Allergy & Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.;Birmingham VA Medical Center, Birmingham, AL, USA. ^[4] Department of Urology, Emory University School of Medicine, Atlanta, GA, USA. ^[5]

关键词 bacterial clearance chronic lung disease neutrophils transcriptional firing

主题词囊性纤维化(Cystic Fibrosis);囊性纤维化跨膜传导调节因子(Cystic Fibrosis Transmembrane Conductance Regulator);人类(Humans);中性白细胞(Neutrophils);铜绿假单胞菌(Pseudomonas aeruginosa);呼吸系统(Respiratory System);痰(Sputum)

DOI 10.1016/j.xcrm.2021.100239

PMID 33948572

发布时间 2024-05-04

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Cell reports. Medicine

2021年2卷4期

100239页

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Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils.

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Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils.

Cell reports. Medicine

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