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Maternal heterozygous mutation in CHEK1 leads to mitotic arrest in human zygotes.

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作者: Beili,Chen [1] ; Jianying,Guo [2] ; Ting,Wang [3] ; Qianhui,Lee [4] ; Jia,Ming [3] ; Fangfang,Ding [4] ; Haitao,Li [5] ; Zhiguo,Zhang [3] ; Lin,Li [1] ; Yunxia,Cao [2] ; Jie,Na [3]
作者单位: Department of Obstetrics and Gynecology, Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. [1] NHC Key Laboratory of study on abnormal gametes and reproductive tract, Anhui Medical University, Hefei, 230032, China. [2] School of Medicine, Tsinghua University, Beijing, 100084, China. [3] Tsinghua-Peking Center for Life Sciences, Beijing, 100084, China. [4] Department of Chemistry, Tsinghua University, Beijing, 100084, China. [5] Department of Obstetrics and Gynecology, Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. zzg_100@163.com. [6] NHC Key Laboratory of study on abnormal gametes and reproductive tract, Anhui Medical University, Hefei, 230032, China. zzg_100@163.com. [7] Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China. linlithu@ccmu.edu.cn. [8] Department of Obstetrics and Gynecology, Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. caoyunxia6@126.com. [9] NHC Key Laboratory of study on abnormal gametes and reproductive tract, Anhui Medical University, Hefei, 230032, China. caoyunxia6@126.com. [10] School of Medicine, Tsinghua University, Beijing, 100084, China. jie.na@tsinghua.edu.cn. [11]
DOI 10.1007/s13238-021-00844-9
PMID 33948904
发布时间 2022-02-28
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