Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity.

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第一作者： Gabriel K,Griffin

第一单位： Broad Institute of MIT and Harvard, Cambridge, MA, USA.

作者： Gabriel K,Griffin ^[1] ; Jingyi,Wu ^[2] ; Arvin,Iracheta-Vellve ^[3] ; James C,Patti ^[1] ; Jeffrey,Hsu ^[2] ; Thomas,Davis ^[1] ; Deborah,Dele-Oni ^[1] ; Peter P,Du ^[1] ; Aya G,Halawi ^[1] ; Jeffrey J,Ishizuka ^[1] ; Sarah Y,Kim ^[1] ; Susan,Klaeger ^[1] ; Nelson H,Knudsen ^[4] ; Brian C,Miller ^[5] ; Tung H,Nguyen ^[1] ; Kira E,Olander ^[1] ; Malvina,Papanastasiou ^[1] ; Suzanna,Rachimi ^[6] ; Emily J,Robitschek ^[1] ; Emily M,Schneider ^[4] ; Mitchell D,Yeary ^[7] ; Margaret D,Zimmer ^[8] ; Jacob D,Jaffe ^[1] ; Steven A,Carr ^[1] ; John G,Doench ^[1] ; W Nicholas,Haining ^[1] ; Kathleen B,Yates ^[1] ; Robert T,Manguso ^[4] ; Bradley E,Bernstein ^[1]

作者单位： Broad Institute of MIT and Harvard, Cambridge, MA, USA. ^[1] Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. ^[2] Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. ^[3] Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA. ^[4] Department of Internal Medicine (Oncology), Yale Cancer Center and Yale School of Medicine, New Haven, CT, USA. ^[5] Department of Medicine and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. ^[6] Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA. ^[7] Department of Immunology and Evergrande Center for Immunological Diseases, Harvard Medical School, Boston, MA, USA. ^[8] Inzen Therapeutics, Cambridge, MA, USA. ^[9] Merck, Boston, MA, USA. ^[10] Broad Institute of MIT and Harvard, Cambridge, MA, USA. rmanguso@mgh.harvard.edu. ^[11] Department of Medicine and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. rmanguso@mgh.harvard.edu. ^[12] Broad Institute of MIT and Harvard, Cambridge, MA, USA. bernstein.bradley@mgh.harvard.edu. ^[13] Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. bernstein.bradley@mgh.harvard.edu. ^[14]