Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid.

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第一作者： Christoph,Dorn

第一单位： Institute of Pharmacy, University of Regensburg, Regensburg, Germany.

作者： Christoph,Dorn ^[1] ; David,Petroff ^[2] ; Melanie,Stoelzel ^[3] ; Martin G,Kees ^[4] ; Alexander,Kratzer ^[5] ; Arne,Dietrich ^[6] ; Charlotte,Kloft ^[7] ; Markus,Zeitlinger ^[8] ; Frieder,Kees ^[9] ; Hermann,Wrigge ^[10] ; Philipp,Simon ^[11]

作者单位： Institute of Pharmacy, University of Regensburg, Regensburg, Germany. ^[1] Clinical Trial Centre, University of Leipzig, Leipzig, Germany.;Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany. ^[2] Department of Anaesthesiology and Intensive Care Medicine, University of Leipzig Medical Centre, Leipzig, Germany. ^[3] Department of Anaesthesiology, University Hospital Regensburg, Regensburg, Germany. ^[4] Hospital Pharmacy, University Hospital Regensburg, Regensburg, Germany. ^[5] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany.;Department of Surgery, University of Leipzig, Leipzig, Germany. ^[6] Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany. ^[7] Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria. ^[8] Department of Pharmacology, University of Regensburg, Regensburg, Germany. ^[9] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany.;Department of Anaesthesiology, Intensive Care and Emergency Medicine, Pain Therapy, Bergmannstrost Hospital Halle, Halle, Germany. ^[10] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany.;Department of Anaesthesiology and Intensive Care Medicine, University of Leipzig Medical Centre, Leipzig, Germany. ^[11]