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A Framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs.

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第一作者： Karli,Gillette

第一单位： Gottfried Schatz Research Center Biophysics, Medical University of Graz, Graz, Austria; BioTechMed-Graz, Graz, Austria.

作者： Karli,Gillette ^[1] ; Matthias A F,Gsell ^[2] ; Anton J,Prassl ^[2] ; Elias,Karabelas ^[3] ; Ursula,Reiter ^[4] ; Gert,Reiter ^[5] ; Thomas,Grandits ^[6] ; Christian,Payer ^[7] ; Darko,Štern ^[8] ; Martin,Urschler ^[7] ; Jason D,Bayer ^[9] ; Christoph M,Augustin ^[2] ; Aurel,Neic ^[10] ; Thomas,Pock ^[6] ; Edward J,Vigmond ^[10] ; Gernot,Plank ^[11]

作者单位： Gottfried Schatz Research Center Biophysics, Medical University of Graz, Graz, Austria; BioTechMed-Graz, Graz, Austria. ^[1] Gottfried Schatz Research Center Biophysics, Medical University of Graz, Graz, Austria. ^[2] Gottfried Schatz Research Center Biophysics, Medical University of Graz, Graz, Austria; Institute for Mathematics and Natural Sciences, University of Graz, Austria. ^[3] Department of Radiology, Medical University of Graz, Graz, Austria. ^[4] Department of Radiology, Medical University of Graz, Graz, Austria; Research and Development, Siemens Healthcare Diagnostics, Graz, Austria. ^[5] Institute of Computer Graphics and Vision, Graz University of Technology, Austria. ^[6] School of Computer Science, The University of Auckland, Auckland, New Zealand. ^[7] Gottfried Schatz Research Center Biophysics, Medical University of Graz, Graz, Austria; Institute of Computer Graphics and Vision, Graz University of Technology, Austria. ^[8] LIRYC Electrophysiology and Heart Modeling Institute, Bordeaux Foundation, Pessac, France. ^[9] NumeriCor Gmbh, Graz, Austria. ^[10] Gottfried Schatz Research Center Biophysics, Medical University of Graz, Graz, Austria; BioTechMed-Graz, Graz, Austria. Electronic address: gernot.plank@medunigraz.at. ^[11]

关键词 Cardiac digital twins Forward ECG modeling Multi-label image segmentation Parameter identification Saltelli sampling Ventricular activation and repolarization sequence

医学主题词计算机模拟(Computer Simulation);心电描记术(Electrocardiography);电生理学技术, 心脏(Electrophysiologic Techniques, Cardiac);心脏(Heart);心室(Heart Ventricles);人类(Humans)

DOI 10.1016/j.media.2021.102080

PMID 33975097

发布时间 2025-05-30

基金项目

I 2760/FWF_/Austrian Science Fund FWF/Austria

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准确一般字义偏差语意偏离译文作用小提交