Slit diaphragm maintenance requires dynamic clathrin-mediated endocytosis facilitated by AP-2, Lap, Aux and Hsc70-4 in nephrocytes.

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作者： Luyao,Wang ^[1] ; Pei,Wen ^[2] ; Joyce,van de Leemput ^[3] ; Zhanzheng,Zhao ^[2] ; Zhe,Han ^[3]

作者单位： Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Eastern Road, Zhengzhou, 450052, Henan, China. ^[1] Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, 670 West Baltimore Street, Baltimore, MD, 21201, USA. ^[2] Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. ^[3] Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Eastern Road, Zhengzhou, 450052, Henan, China. zhanzhengzhao@zzu.edu.cn. ^[4] Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, 670 West Baltimore Street, Baltimore, MD, 21201, USA. zhan@som.umaryland.edu. ^[5] Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. zhan@som.umaryland.edu. ^[6]

关键词 AP-2 complex Auxilin Clathrin Drosophila Endocytosis Hsc70-4 Lap Nephrocyte Shi Slit diaphragm

DOI 10.1186/s13578-021-00595-4

PMID 33975644

发布时间 2021-06-12

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