换一批Nanomedicine for acute respiratory distress syndrome: The latest application, targeting strategy, and rational design.
第一作者：
Qi,Qiao
第一单位：
Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.
作者：
关键词
ACE2, angiotensin-converting enzyme 2AEC II, alveolar type II epithelial cellsAM, alveolar macrophagesARDS, acute respiratory distress syndromeAcute lung injuryAcute respiratory distress syndromeAnti-inflammatory therapyBALF, bronchoalveolar lavage fluidBSA, bovine serum albuminCD, cyclodextrinCLP, cecal ligation and perforationCOVID-19COVID-19, coronavirus disease 2019DOPE, phosphatidylethanolamineDOTAP, 1-diolefin-3-trimethylaminopropaneDOX, doxorubicinDPPC, dipalmitoylphosphatidylcholineDrug deliveryECM, extracellular matrixELVIS, extravasation through leaky vasculature and subsequent inflammatory cell-mediated sequestrationEPCs, endothelial progenitor cellsEPR, enhanced permeability and retentionEVs, extracellular vesiclesEphA2, ephrin type-A receptor 2Esbp, E-selectin-binding peptideFcgR, Fcγ receptorGNP, peptide-gold nanoparticleH2O2, hydrogen peroxideHO-1, heme oxygenase-1ICAM-1, intercellular adhesion molecule-1IKK, IκB kinaseIL, interleukinLPS, lipopolysaccharideMERS, Middle East respiratory syndromeMPMVECs, mouse pulmonary microvascular endothelial cellsMPO, myeloperoxidaseMSC, mesenchymal stem cellsNAC, N-acetylcysteineNE, neutrophil elastaseNETs, neutrophil extracellular trapsNF-κB, nuclear factor-κBNanomedicinePC, phosphatidylcholinePCB, poly(carboxybetaine)PDA, polydopaminePDE4, phosphodiesterase 4PECAM-1, platelet-endothelial cell adhesion moleculePEG, poly(ethylene glycol)PEI, polyetherimidePEVs, platelet-derived extracellular vesiclesPLGA, poly(lactic-co-glycolic acid)PS-PEG, poly(styrene-b-ethylene glycol)Pathophysiologic featureRBC, red blood cellsRBD, receptor-binding domainsROS, reactive oxygen speciesS1PLyase, sphingosine-1-phosphate lyaseSARS, severe acute respiratory syndromeSARS-CoV-2, severe acute respiratory syndrome coronavirus 2SDC1, syndecan-1SORT, selective organ targetingSP, surfactant proteinSe, seleniumSiglec, sialic acid-binding immunoglobulin-like lectinTLR, toll-like receptorTNF-α, tumor necrosis factor-αTPP, triphenylphosphonium cationTargeting strategyYSA, YSAYPDSVPMMScRGD, cyclic arginine glycine-d-aspartic acidiNOS, inducible nitric oxide synthaserSPANb, anti-rat SP-A nanobodyscFv, single chain variable fragments
DOI
10.1016/j.apsb.2021.04.023
PMID
33977080
发布时间
2024-04-03
- 浏览2
Acta pharmaceutica Sinica. B
2021年11卷10期
3060-3091页
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