Selumetinib normalizes Ras/MAPK signaling in clinically relevant neurofibromatosis type 1 minipig tissues in vivo.

导出 LinkOut

翻译打印收藏纠错

第一作者： Sara H,Osum

第一单位： Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.

作者： Sara H,Osum ^[1] ; Alexander W,Coutts ^[2] ; Dylan J,Duerre ^[2] ; Barbara R,Tschida ^[2] ; Mark N,Kirstein ^[1] ; James,Fisher ^[3] ; W Robert,Bell ^[1] ; Oona,Delpuech ^[3] ; Paul D,Smith ^[1] ; Brigitte C,Widemann ^[4] ; Christopher L,Moertel ^[5] ; David A,Largaespada ^[5] ; Adrienne L,Watson ^[6]

作者单位： Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA. ^[1] Recombinetics Inc., Eagan, Minnesota, USA. ^[2] Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota, USA. ^[3] Division of Neuropathology, Department of Lab Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA. ^[4] Oncology R&D, AstraZeneca, Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. ^[5] Pediatric Oncology Branch, Rare Tumor Initiative, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA. ^[6]

关键词 MEK inhibitor neurofibromatosis type 1 pharmacodynamics pharmacokinetics selumetinib

DOI 10.1093/noajnl/vdab020

PMID 33978635

发布时间 2024-05-04

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交

浏览0

Neuro-oncology advances

vdab020页

相似文献

中文期刊
外文期刊
学位论文
会议论文

检索历史清除

Selumetinib normalizes Ras/MAPK signaling in clinically relevant neurofibromatosis type 1 minipig tissues in vivo.

Neuro-oncology advances

相似文献

Neuro-oncology advances

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Selumetinib normalizes Ras/MAPK signaling in clinically relevant neurofibromatosis type 1 minipig tissues in vivo.

Neuro-oncology advances

相似文献

Neuro-oncology advances

相关期刊

检索历史清除