Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations.

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第一作者： Daniel J,Kramer

第一单位： Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.

作者： Daniel J,Kramer ^[1] ; Erin E,Aisenberg ^[2] ; Polina,Kosillo ^[1] ; Drew,Friedmann ^[3] ; David A,Stafford ^[1] ; Angus Yiu-Fai,Lee ^[4] ; Liqun,Luo ^[3] ; Dirk,Hockemeyer ^[5] ; John,Ngai ^[6] ; Helen S,Bateup ^[7]

作者单位： Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA. ^[1] Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA. ^[2] Howard Hughes Medical Institute and Department of Biology, Stanford University, Stanford, CA 94305, USA. ^[3] Cancer Research Laboratory, University of California, Berkeley, Berkeley, CA 94720, USA. ^[4] Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA. ^[5] Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA. ^[6] Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: bateup@berkeley.edu. ^[7]

关键词 DAT DAT-dopamine neurons Flp recombinase Neurod6 TrailMap intersectional genetics nucleus accumbens substantia nigra pars compacta ventral tegmental area

主题词动物(Animals);细胞系(Cell Line);多巴胺质膜转运蛋白质类(Dopamine Plasma Membrane Transport Proteins);人类(Humans);小鼠(Mice)

DOI 10.1016/j.celrep.2021.109123

PMID 33979604

发布时间 2022-02-09

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