An Optical-Flow-Based Method to Quantify Dynamic Behavior of Human Pluripotent Stem Cell-Derived Cardiomyocytes in Disease Modeling Platforms.

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第一作者： Mohammad,Izadifar

第一单位： Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. mohammad.izadifar@utoronto.ca.

作者： Mohammad,Izadifar ^[1] ; Tünde,Berecz ^[2] ; Ágota,Apáti ^[2] ; Andras,Nagy ^[3]

作者单位： Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. mohammad.izadifar@utoronto.ca. ^[1] Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary. ^[2] Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. ^[3] Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC, Australia. ^[4] Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON, Canada. ^[5] Institute of Medical Science, University of Toronto, Toronto, ON, Canada. ^[6]

关键词 Cardiomyocytes Cardiotoxicity Contractile phenotype Disease modeling Induced pluripotent stem cells Optical flow imaging Quantitative imaging Video microscopy

主题词细胞分化(Cell Differentiation);药物评价, 临床前(Drug Evaluation, Preclinical);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);肌收缩(Muscle Contraction);肌细胞, 心脏(Myocytes, Cardiac);多潜能干细胞(Pluripotent Stem Cells)

DOI 10.1007/7651_2021_382

PMID 33982275

发布时间 2022-06-27

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准确一般字义偏差语意偏离译文作用小提交