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首页> Gene> Degradation of p53 by HPV16-E6 variants isolated from cervical cancer specimens of Moroccan women.

Degradation of p53 by HPV16-E6 variants isolated from cervical cancer specimens of Moroccan women.

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作者： Khaoula,Hadami ^[1] ; Charles,Saby ^[2] ; Nadia,Dakka ^[3] ; Guillaume,Collin ^[2] ; Mohammed,Attaleb ^[4] ; Meriem,Khyatti ^[5] ; Abdelkarim,Filali-Maltouf ^[6] ; Hamid,Morjani ^[2] ; Mohammed,El Mzibri ^[7]

作者单位： Biology and Medical Research Unit, National Centre for Energy, Nuclear Sciences and Techniques (CNESTEN), Rabat, Morocco; Biology of Human Pathologies Laboratory, Faculty of Sciences, Mohammed V University, Rabat, Morocco. ^[1] BioSpecT-EA7506 Unit, Faculty of Pharmacy, Reims Champagne-Ardenne University, Reims, France. ^[2] Biology of Human Pathologies Laboratory, Faculty of Sciences, Mohammed V University, Rabat, Morocco. ^[3] Biology and Medical Research Unit, National Centre for Energy, Nuclear Sciences and Techniques (CNESTEN), Rabat, Morocco. ^[4] Oncovirology Laboratory, Pasteur Institute, Casablanca, Morocco. ^[5] Microbiology and Molecular Biology Laboratory, Faculty of Sciences, Mohammed V University, Rabat, Morocco. ^[6] Biology and Medical Research Unit, National Centre for Energy, Nuclear Sciences and Techniques (CNESTEN), Rabat, Morocco. Electronic address: elmzibri@cnesten.org.ma. ^[7]

关键词 C33A cells Cervical cancer HPV16-E6 variants Moroccan women P53 degradation

主题词成年人(Adult);老年人(Aged);细胞系(Cell Line);女(雌)性(Female);遗传变异(Genetic Variation);人乳头瘤病毒16(Human papillomavirus 16);人类(Humans);中年人(Middle Aged);摩洛哥(Morocco);突变(Mutation);癌基因蛋白质类, 病毒性(Oncogene Proteins, Viral);乳头状瘤病毒感染(Papillomavirus Infections);多态现象, 遗传(Polymorphism, Genetic);阻遏蛋白质类(Repressor Proteins);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);宫颈肿瘤(Uterine Cervical Neoplasms)

DOI 10.1016/j.gene.2021.145709

PMID 33984442

发布时间 2021-07-06

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