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Cell-Type Specific Changes in DNA Methylation of <i>SNCA</i> Intron 1 in Synucleinopathy Brains.

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第一作者： Jeffrey,Gu

第一单位： Division of Translational Brain Sciences, Department of Neurology, Duke University Medical Center, Durham, NC, United States.;Center for Genomic and Computational Biology, Duke University Medical Center, Durham, NC, United States.

作者： Jeffrey,Gu ^[1] ; Julio,Barrera ^[1] ; Young,Yun ^[1] ; Susan K,Murphy ^[2] ; Thomas G,Beach ^[3] ; Randy L,Woltjer ^[4] ; Geidy E,Serrano ^[3] ; Boris,Kantor ^[5] ; Ornit,Chiba-Falek ^[1]

作者单位： Division of Translational Brain Sciences, Department of Neurology, Duke University Medical Center, Durham, NC, United States.;Center for Genomic and Computational Biology, Duke University Medical Center, Durham, NC, United States. ^[1] Division of Reproductive Sciences, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, United States. ^[2] Banner Sun Health Research Institute, Sun City, AZ, United States. ^[3] Layton Aging and Alzheimer's Disease Center, Department of Pathology, Oregon Health & Science University, Portland, OR, United States. ^[4] Viral Vector Core, Duke University Medical Center, Durham, NC, United States.;Department of Neurobiology, Duke University Medical Center, Durham, NC, United States. ^[5]

关键词 DNA methylation Parkinson’s disease bisulfite pyrosequencing dementia with Lewy body fluorescence-activated nuclei sorting α-synuclein gene (SNCA)

DOI 10.3389/fnins.2021.652226

PMID 33994928

发布时间 2024-04-12

基金项目

P30 AG008017/AG/NIA NIH HHS/United States P30 AG066518/AG/NIA NIH HHS/United States RF1 NS113548/NS/NINDS NIH HHS/United States

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