A Single Mutation in the Outer Lipid-Facing Helix of a Pentameric Ligand-Gated Ion Channel Affects Channel Function Through a Radially-Propagating Mechanism.

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作者： Alessandro,Crnjar ^[1] ; Susanne M,Mesoy ^[2] ; Sarah C R,Lummis ^[2] ; Carla,Molteni ^[1]

作者单位： Physics Department, King's College London, London, United Kingdom. ^[1] Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom. ^[2]

关键词 5-HT3 receptors Cys-loop receptors M4 helix molecular dynamics mutagenesis pentameric ligand-gated ion channels

DOI 10.3389/fmolb.2021.644720

PMID 33996899

发布时间 2024-04-02

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Frontiers in molecular biosciences

2021年8卷

644720页

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A Single Mutation in the Outer Lipid-Facing Helix of a Pentameric Ligand-Gated Ion Channel Affects Channel Function Through a Radially-Propagating Mechanism.

Frontiers in molecular biosciences

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Frontiers in molecular biosciences

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A Single Mutation in the Outer Lipid-Facing Helix of a Pentameric Ligand-Gated Ion Channel Affects Channel Function Through a Radially-Propagating Mechanism.

Frontiers in molecular biosciences

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Frontiers in molecular biosciences

相关期刊

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