New quinoxalin-1,3,4-oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies.

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作者： Roghieh,Mirzazadeh ^[1] ; Mohammad S,Asgari ^[2] ; Ebrahim,Barzegari ^[3] ; Keyvan,Pedrood ^[4] ; Maryam,Mohammadi-Khanaposhtani ^[5] ; Maedeh,Sherafati ^[4] ; Bagher,Larijani ^[4] ; Hossein,Rastegar ^[6] ; Hojjat,Rahmani ^[7] ; Mohammad,Mahdavi ^[4] ; Parham,Taslimi ^[8] ; Eda M,Üç ^[9] ; İlhami,Gulçin ^[9]

作者单位： Department of Biochemistry, Pasteur Institute of Iran, Tehran, Iran. ^[1] Department of Chemistry, Iran University of Science and Technology, Tehran, Iran. ^[2] Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. ^[3] Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. ^[4] Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. ^[5] Cosmetic Products Research Center, Iranian Food and Drug Administration, MOHE, Tehran, Iran. ^[6] Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. ^[7] Department of Biotechnology, Faculty of Science, Bartin University, Bartin, Turkey. ^[8] Department of Chemistry, Faculty of Science, Ataturk University, Erzurum, Turkey. ^[9]

关键词 1,3,4-oxadiazole carbonic anhydrase cholinesterase quinoxalin α-glucosidase

主题词碳酸酐酶抑制剂(Carbonic Anhydrase Inhibitors);胆碱酯酶抑制剂(Cholinesterase Inhibitors);人类(Humans);模型, 分子(Models, Molecular);恶二唑类(Oxadiazoles);喹恶啉类(Quinoxalines);构效关系(Structure-Activity Relationship)

DOI 10.1002/ardp.202000471

PMID 33999440

发布时间 2022-01-12

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