PRICKLE1, a Wnt/PCP signaling component, is overexpressed and associated with inferior prognosis in acute myeloid leukemia.

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作者： Duanfeng,Jiang ^[1] ; Yanjuan,He ^[2] ; Qiuyu,Mo ^[3] ; Enyi,Liu ^[2] ; Xin,Li ^[1] ; Lihua,Huang ^[4] ; Qin,Zhang ^[1] ; Fangping,Chen ^[1] ; Yan,Li ^[2] ; Haigang,Shao ^[5]

作者单位： Department of Hematology, The 3rd Xiangya Hospital, Central South University, Changsha, Hunan, China. ^[1] Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China. ^[2] Department of Hematology, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China. ^[3] Center for Medical Experiments, The 3rd Xiangya Hospital, Central South University, Changsha, Hunan, China. ^[4] Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, China. xyaliyan@163.com. ^[5] Department of Hematology, The 3rd Xiangya Hospital, Central South University, Changsha, Hunan, China. xya3shg@163.com. ^[6]

关键词 Acute myeloid leukemia PRICKLE1 Prognosis Wnt/PCP signaling

主题词基因表达调控, 白血病(Gene Expression Regulation, Leukemic);人类(Humans);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);突变(Mutation);预后(Prognosis);缓解诱导(Remission Induction);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)

DOI 10.1186/s12967-021-02873-8

PMID 34001134

发布时间 2022-05-31

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