Blockage of the JAK/STAT3 signaling pathway in multiple myeloma by leelamine.

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作者： Young Yun,Jung ^[1] ; Jae-Young,Um ^[1] ; Omaima,Nasif ^[2] ; Sulaiman Ali,Alharbi ^[3] ; Gautam,Sethi ^[4] ; Kwang Seok,Ahn ^[5]

作者单位： Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. ^[1] Department of Physiology, College of Medicine, King Saud University, [Medical City], King Khalid University Hospital, PO Box-2925, Riyadh -11461, Saudi Arabia. ^[2] Department of Botany and Microbiology, College of Science, King Saud University, Riyadh -11451, Saudi Arabia. ^[3] Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore. Electronic address: phcgs@nus.edu.sg. ^[4] Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: ksahn@khu.ac.kr. ^[5]

关键词 Apoptosis Leelamine MM PTP epsilon STAT3

主题词抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控(Gene Expression Regulation);人类(Humans);Janus激酶1(Janus Kinase 1);Janus激酶2(Janus Kinase 2);多发性骨髓瘤(Multiple Myeloma);磷酰化(Phosphorylation);STAT3转录因子(STAT3 Transcription Factor);信号传导(Signal Transduction)

DOI 10.1016/j.phymed.2021.153574

PMID 34006448

发布时间 2021-06-30

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Phytomedicine

2021年87卷

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Blockage of the JAK/STAT3 signaling pathway in multiple myeloma by leelamine.

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Blockage of the JAK/STAT3 signaling pathway in multiple myeloma by leelamine.

Phytomedicine

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Phytomedicine

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