Small-molecule inhibitor targeting the Hsp70-Bim protein-protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance.

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第一作者： Ting,Song

第一单位： State Key Laboratory of Fine Chemicals, Zhang Dayu School of Chemistry, Dalian University of Technology, Dalian, Liaoning, China.

作者： Ting,Song ^[1] ; Yafei,Guo ^[2] ; Zuguang,Xue ^[3] ; Zongwei,Guo ^[2] ; Ziqian,Wang ^[1] ; Donghai,Lin ^[4] ; Hong,Zhang ^[2] ; Hao,Pan ^[1] ; Xiaodong,Zhang ^[1] ; Fangkui,Yin ^[1] ; Hang,Wang ^[5] ; Laura Bonnette,Uwituze ^[1] ; Zhichao,Zhang ^[6]

作者单位： State Key Laboratory of Fine Chemicals, Zhang Dayu School of Chemistry, Dalian University of Technology, Dalian, Liaoning, China. ^[1] School of Life Science and Technology, Dalian University of Technology, Dalian, Liaoning, China. ^[2] Department of Hematology, Second Affiliated Hospital, Dalian Medical University, Dalian, Liaoning, China. ^[3] The Key Laboratory for Chemical Biology of Fujian Province, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian, China. dhlin@xmu.edu.cn. ^[4] School of Innovation and Entrepreneurship, Dalian University of Technology, Dalian, Liaoning, China. ^[5] State Key Laboratory of Fine Chemicals, Zhang Dayu School of Chemistry, Dalian University of Technology, Dalian, Liaoning, China. zczhang@dlut.edu.cn. ^[6]