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首页> Cancer science> A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy.

A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy.

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作者： Akemi,Kosaka ^[1] ; Yuki,Yajima ^[1] ; Mayumi,Hatayama ^[2] ; Katsuya,Ikuta ^[2] ; Takaaki,Sasaki ^[3] ; Noriko,Hirai ^[3] ; Syunsuke,Yasuda ^[3] ; Marino,Nagata ^[1] ; Ryusuke,Hayashi ^[4] ; Shohei,Harabuchi ^[4] ; Kenzo,Ohara ^[4] ; Mizuho,Ohara ^[1] ; Takumi,Kumai ^[4] ; Kei,Ishibashi ^[3] ; Yui,Hirata-Nozaki ^[4] ; Toshihiro,Nagato ^[1] ; Kensuke,Oikawa ^[1] ; Yasuaki,Harabuchi ^[4] ; Esteban,Celis ^[5] ; Toshikatsu,Okumura ^[2] ; Yoshinobu,Ohsaki ^[3] ; Hiroya,Kobayashi ^[1] ; Takayuki,Ohkuri ^[1]

作者单位： Department of Pathology, Asahikawa Medical University, Asahikawa, Japan. ^[1] Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan. ^[2] Respiratory Center, Asahikawa Medical University, Asahikawa, Japan. ^[3] Department of Otolaryngology, Head and Neck Surgery, Asahikawa Medical University, Asahikawa, Japan. ^[4] Georgia Cancer Center, Augusta University Medical College of Georgia, Augusta, GA, USA. ^[5]

关键词 DNA methylation cancer immunoediting cancer immunotherapy stealth antigens tumor immunoescape

主题词动物(Animals);抗原, 肿瘤(Antigens, Neoplasm);载体蛋白质类(Carrier Proteins);细胞系, 肿瘤(Cell Line, Tumor);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);表位, T淋巴细胞(Epitopes, T-Lymphocyte);人类(Humans);免疫疗法(Immunotherapy);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);肿瘤(Neoplasms);精浆蛋白质类(Seminal Plasma Proteins);T淋巴细胞, 辅助诱导(T-Lymphocytes, Helper-Inducer);肿瘤逃逸(Tumor Escape)

DOI 10.1111/cas.14973

PMID 34009705

发布时间 2021-07-14

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准确一般字义偏差语意偏离译文作用小提交

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Cancer science

Cancer science

2021年112卷7期

2705-2713页

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