Positivity of oligoclonal bands in the cerebrospinal fluid predisposed to metabolic changes and rearrangement of inhibitory/excitatory neurotransmitters in subcortical brain structures in multiple sclerosis.

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作者： Ema,Kantorová ^[1] ; Petra,Hnilicová ^[2] ; Wolfgang,Bogner ^[3] ; Marián,Grendár ^[4] ; Daniel,Čierny ^[5] ; Eva,Hečková ^[6] ; Bernhard,Strasser ^[7] ; Róbert,Ružinák ^[8] ; Kamil,Zeleňák ^[9] ; Egon,Kurča ^[10]

作者单位： Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia. Electronic address: ema.kantorova@uniba.sk. ^[1] Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia. Electronic address: petra.hnilicova@uniba.sk. ^[2] Department of Biomedical Imaging and Image-Guided Therapy, High-field MR Center, Medical University of Vienna, 1090 Vienna, Austria. Electronic address: wolfgang.bogner@meduniwien.ac.at. ^[3] Biomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia. Electronic address: marian.grendar@uniba.sk. ^[4] Department of Clinical Biochemistry, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia. Electronic address: daniel.cierny@uniba.sk. ^[5] Department of Biomedical Imaging and Image-Guided Therapy, High-field MR Center, Medical University of Vienna, 1090 Vienna, Austria. Electronic address: eva.heckova@meduniwien.ac.at. ^[6] Department of Biomedical Imaging and Image-Guided Therapy, High-field MR Center, Medical University of Vienna, 1090 Vienna, Austria. Electronic address: bernhard.strasser@meduniwien.ac.at. ^[7] Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia. Electronic address: robert.ruzinak@gmail.com. ^[8] Clinic of Radiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia. Electronic address: kamil.zelenak@uniba.sk. ^[9] Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia. Electronic address: egon.kurca@uniba.sk. ^[10]

关键词 Cerebrospinal fluid Multiple sclerosis Oligoclonal bands Proton magnetic resonance spectroscopy Subcortical gray/white matter

主题词脑(Brain);人类(Humans);多发性硬化(Multiple Sclerosis);神经递质药(Neurotransmitter Agents);寡克隆区带(Oligoclonal Bands);γ氨基丁酸(gamma-Aminobutyric Acid)

DOI 10.1016/j.msard.2021.102978

PMID 34015640

发布时间 2021-07-06

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