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A nanogel-based trivalent PspA nasal vaccine protects macaques from intratracheal challenge with pneumococci.

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第一作者: Rika,Nakahashi-Ouchida
第一单位: Division of Mucosal Vaccines, International Research and Development Center for Mucosal Vaccine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan; Department of Mucosal Immunology, IMSUT Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
作者单位: Division of Mucosal Vaccines, International Research and Development Center for Mucosal Vaccine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan; Department of Mucosal Immunology, IMSUT Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan. [1] Division of Mucosal Vaccines, International Research and Development Center for Mucosal Vaccine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan. [2] Division of Mucosal Vaccines, International Research and Development Center for Mucosal Vaccine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan; HanaVax Inc., Tokyo 103-0012, Japan. [3] Department of Medical Science Project Planning and Support, The Corporation for Production and Research of Laboratory Primates, Ibaraki, 305-0843, Japan. [4] Toko Yakuhin Kogyo Co., Ltd., 930-0211, Japan. [5] Department of Mucosal Immunology, IMSUT Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan; Faculty of Medicine, Department of Otorhinolaryngology and Head and Neck Surgery, Oita University, Oita 879-5593, Japan. [6] Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan. [7] Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294-2170, United States. [8] Laboratory of Immunoregulation and Vaccine Research, Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, 305-0843, Japan. [9] Department of Mucosal Immunology, IMSUT Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan; HanaVax Inc., Tokyo 103-0012, Japan; Mucosal Immunology and Allergy Therapeutics, Institute for Global Prominent Research, Chiba University, Chiba 263-8522, Japan; CU-UCSD Center for Mucosal Immunology, Allergy and Vaccine (cMAV), Division of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, CA 92093-0063, United States. Electronic address: kiyono@ims.u-tokyo.ac.jp. [10]
DOI 10.1016/j.vaccine.2021.04.069
PMID 34016473
发布时间 2021-07-08
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Vaccine

Vaccine

2021年39卷25期

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