首页> Bioorganic chemistry> Synthesis, In-vitro evaluation and molecular docking studies of oxoindolin phenylhydrazine carboxamides as potent and selective inhibitors of ectonucleoside triphosphate diphosphohydrolase (NTPDase).

Synthesis, In-vitro evaluation and molecular docking studies of oxoindolin phenylhydrazine carboxamides as potent and selective inhibitors of ectonucleoside triphosphate diphosphohydrolase (NTPDase).

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第一作者： Saira,Afzal

第一单位： Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, Pakistan.

作者： Saira,Afzal ^[1] ; Mariya,Al-Rashida ^[2] ; Abdul,Hameed ^[1] ; Julie,Pelletier ^[3] ; Jean,Sévigny ^[4] ; Jamshed,Iqbal ^[5]

作者单位： Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, Pakistan. ^[1] Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan. ^[2] Centre de recherche du CHU de Québec, Université Laval, Québec City, QC, Canada. ^[3] Centre de recherche du CHU de Québec, Université Laval, Québec City, QC, Canada; Département de Microbiologie-Infectiologie et d'Immunologie, Faculté de Médecine, Université Laval, Québec City, QC, Canada. ^[4] Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, Pakistan. Electronic address: drjamshed@cuiatd.edu.pk. ^[5]

关键词 Carboxamide Isatin Molecular docking Nucleoside triphosphate diphosphohydrolase inhibitors Oxoindolin