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首页> Biochemical and biophysical research communications> Targeting NF-κB-dependent alkaliptosis for the treatment of venetoclax-resistant acute myeloid leukemia cells.

Targeting NF-κB-dependent alkaliptosis for the treatment of venetoclax-resistant acute myeloid leukemia cells.

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作者： Shan,Zhu ^[1] ; Jiao,Liu ^[2] ; Rui,Kang ^[3] ; Minghua,Yang ^[4] ; Daolin,Tang ^[5]

作者单位： Department of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China. ^[1] The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, China. ^[2] Department of Surgery, UT Southwestern Medical Center, Dallas, TX, 75390, USA. ^[3] Department of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China. Electronic address: yangminghua@csu.edu.cn. ^[4] Department of Surgery, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Electronic address: daolin.tang@utsouthwestern.edu. ^[5]

关键词 Acute myeloid leukemia Alkaliptosis BCL2 Drug resistance Venetoclax

主题词碱类(Alkalies);氨基喹啉类(Aminoquinolines);动物(Animals);细胞凋亡(Apoptosis);苯甲酰胺类(Benzamides);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);小鼠, 裸(Mice, Nude);NF-κB(NF-kappa B);磺胺类(Sulfonamides);bcl-X蛋白质(bcl-X Protein);小鼠(Mice)

DOI 10.1016/j.bbrc.2021.05.049

PMID 34034094

发布时间 2024-02-26

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Biochemical and biophysical research communications

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