换一批Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis.
第一作者：
Chao,Ma
第一单位：
Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.;Sanders-Brown Center on Aging, Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, United States.
作者：
医学主题词
阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);动物(Animals);精氨酸酶(Arginase);脑(Brain);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);基因表达谱(Gene Expression Profiling);基因调控网络(Gene Regulatory Networks);单倍剂量不足(Haploinsufficiency);人类(Humans);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);小神经胶质细胞(Microglia);突变(Mutation);髓系细胞(Myeloid Cells);神经变性(Nerve Degeneration);小鼠(Mice)
DOI
10.3389/fimmu.2021.628156
PMID
34046031
发布时间
2024-02-26
基金项目
R01 AG051500/AG/NIA NIH HHS/United States
F31 NS110264/NS/NINDS NIH HHS/United States
R01 AI095307/AI/NIAID NIH HHS/United States
R01 NS091582/NS/NINDS NIH HHS/United States
R01 AG054559/AG/NIA NIH HHS/United States
R21 AG055996/AG/NIA NIH HHS/United States
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Frontiers in immunology
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