首页> Journal of controlled release : official journal of the Controlled Release Society> Redox-responsive nanoassembly restrained myeloid-derived suppressor cells recruitment through autophagy-involved lactate dehydrogenase A silencing for enhanced cancer immunochemotherapy.

Redox-responsive nanoassembly restrained myeloid-derived suppressor cells recruitment through autophagy-involved lactate dehydrogenase A silencing for enhanced cancer immunochemotherapy.

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第一作者： Chunyu,Xia

第一单位： Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.

作者： Chunyu,Xia ^[1] ; Man,Li ^[1] ; Guangyao,Ran ^[1] ; Xuhui,Wang ^[1] ; Zhengze,Lu ^[1] ; Ting,Li ^[1] ; Xian,Tang ^[1] ; Zhirong,Zhang ^[1] ; Qin,He ^[2]

作者单位： Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. ^[1] Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. Electronic address: qinhe@scu.edu.cn. ^[2]

关键词 AMPK-ULK1 pathway Autophagy Cytokines-mediated MDSCs recruitment Immune microenvironment remodeling LDHA silencing Redox-responsive siRNA release